abstract：INTRODUCTION:The National Healthcare Safety Network (NHSN) Hemovigilance Module (HM) collects data on the frequency, severity, and imputability of transfusion-associated adverse events. These events contribute to significant morbidity and mortality among transfusion patients. We report results from the first systematic...

journal_title：Transfusion

authors： Edens C,Haass KA,Cumming M,Osinski A,O'Hearn L,Passanisi K,Eaton L,Visintainer P,Savinkina A,Kuehnert MJ,Basavaraju SV,Andrzejewski C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Biological and technical variability has been increasingly appreciated as a key factor impacting red blood cell (RBC) storability and, potentially, transfusion outcomes. Here, we performed metabolomics analyses to investigate the impact of factors other than storage duration on the metabolic phenotypes of st...

journal_title：Transfusion

authors： D'Alessandro A,Culp-Hill R,Reisz JA,Anderson M,Fu X,Nemkov T,Gehrke S,Zheng C,Kanias T,Guo Y,Page G,Gladwin MT,Kleinman S,Lanteri M,Stone M,Busch M,Zimring JC,Recipient Epidemiology and Donor Evaluation Study-III (REDS-

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Almost 20% of parvovirus B19 foetal infections require intrauterine transfusions. In addition, myocardial dysfunction has been observed in severe parvovirus B19 infections. One objective of an intrauterine exchange transfusion (IUET) is to avoid an overload during the transfusion. Our aim was to study the ob...

journal_title：Transfusion

authors： Vanspranghels R,Houfflin-Debarge V,Vaast P,Coulon C,Clouqueur E,Hanssens S,Rakza T,Subtil D,Garabedian C

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Access to a safe, adequate blood supply has proven challenging in sub-Saharan Africa, where systemic deficiencies spanning policy, collections, testing, and posttransfusion surveillance have long been recognized. Progress in transfusion safety in the early 2000s was in large part due to intervention by the W...

journal_title：Transfusion

authors： Weimer A,Tagny CT,Tapko JB,Gouws C,Tobian AAR,Ness PM,Bloch EM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Hemolysis at the time of graft infusion is one of the immediate complications in major ABO-incompatible allogeneic hematopoietic stem cell transplants (HSCTs). We conducted a retrospective analysis to evaluate the efficacy of donor-type fresh frozen plasma (FFP) in reducing isohemagglutinin titer and prevent...

journal_title：Transfusion

authors： Quek J,Lee JJ,Lim FL,Diong C,Goh YT,Gopalakrishnan S,Ho A,Hwang W,Koh M,Loh Y,Linn YC

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The classification of many new cases of hepatitis virus infection as overt hepatitis does not reflect the true incidence of infection because the disease takes an asymptomatic course in some cases. In this retrospective cohort study, we aimed to estimate the incidence rates of new hepatitis C virus (HCV) inf...

journal_title：Transfusion

authors： Uchida S,Satake M,Kurisu A,Sugiyama A,Ko K,Akita T,Tanaka J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Uncontrollable bleeding is the leading cause of death in traumatically injured patients. The extent to which direct factor Xa inhibitors interfere with the applied resuscitation measures is presently unknown. STUDY DESIGN AND METHODS:In this study, we investigated the effect of the resuscitation fluids sali...

journal_title：Transfusion

authors： Helin TA,Zuurveld M,Manninen M,Meijers JCM,Lassila R,Brinkman HJM

更新日期：2018-12-01 00:00:00

abstract：:Immune-deficient patients depend on the antibodies in pooled human immunoglobulin G (IgG) preparations to remain free from serious infections. The potency of IgG preparations is therefore an ongoing concern. The use of pooled IgG to prevent infection is based on the concept that healthy adults have recovered from infe...

journal_title：Transfusion

authors： Berger M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:We assessed donor return rates, donation frequency, and factors related to the evolution of ferritin levels 2 years after entering donors into a large operational study of ferritin testing. STUDY DESIGN AND METHODS:Ferritin testing was done on donors from representative clinics (n = 12,595). Low-ferritin do...

journal_title：Transfusion

authors： Goldman M,Uzicanin S,Osmond L,Yi QL,Scalia V,O'Brien SF

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The 1000 Genomes Project provides a database of genomic variants from whole genome sequencing of 2504 individuals across five continental superpopulations. This database can enrich our background knowledge of worldwide blood group variant geographic distribution and identify novel variants of potential clini...

journal_title：Transfusion

authors： Montemayor-Garcia C,Karagianni P,Stiles DA,Reese EM,Smellie DA,Loy DA,Levy KY,Nwokocha M,Bueno MU,Miller JL,Klein HG

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The anti-CD20 monoclonal antibody rituximab has immune-modulatory effects similar to intravenous immunoglobulin (IVIG). We performed a systematic review and meta-analysis to determine the efficacy and safety of rituximab in autoimmune diseases that are also treated with IVIG. STUDY DESIGN AND METHODS:The mo...

journal_title：Transfusion

authors： MacIsaac J,Siddiqui R,Jamula E,Li N,Baker S,Webert KE,Evanovitch D,Heddle NM,Arnold DM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Nonenveloped transfusion-transmissible viruses such as hepatitis A virus (HAV) and hepatitis E virus (HEV) are resistant to many of the common virus inactivation procedures for blood products. This study investigated the pathogen inactivation (PI) efficacy of the THERAFLEX UV-Platelets system against two non...

journal_title：Transfusion

authors： Gravemann U,Handke W,Lambrecht B,Schmidt JP,Müller TH,Seltsam A

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Decisions on prophylactic platelet (PLT) transfusions are generally based on the recipient's PLT count, but few clinicians are aware of precision and accuracy of the PLT counting methods used by the clinical laboratory. Each PLT counting technology has its specific inaccuracy, especially in thrombocytopenic ...

journal_title：Transfusion

authors： Hummel K,Sachse M,Hoffmann JJML,van Dun LPJM

更新日期：2018-10-01 00:00:00

abstract：:ADAMTS13 is an enzyme that acts by cleaving prothrombotic von Willebrand factor (VWF) multimers from the vasculature in a highly regulated manner. In pathologic states such as thrombotic thrombocytopenic purpura (TTP) and other thrombotic microangiopathies (TMAs), VWF can bind to the endothelium and form large multime...

journal_title：Transfusion

authors： Plautz WE,Raval JS,Dyer MR,Rollins-Raval MA,Zuckerbraun BS,Neal MD

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:There is an increasing awareness to integrate patient blood management (PBM) within routine surgical care. Limited information about the implementation of PBM in colorectal cancer surgery is available. This is curious, as preoperative anemia, associated with increased morbidity, is highly prevalent in colo...

journal_title：Transfusion

authors： Wilson MJ,Koopman-van Gemert AWMM,Harlaar JJ,Jeekel J,Zwaginga JJ,Schipperus M

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The serological safety of transfusing ≤4 units of low titer group O whole blood (LTOWB) in civilian trauma patients has been demonstrated. This study investigated clinical outcomes of LTOWB recipients compared to patients who received only conventional blood components during their resuscitation. STUDY DESI...

journal_title：Transfusion

authors： Seheult JN,Anto V,Alarcon LH,Sperry JL,Triulzi DJ,Yazer MH

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The 2016 Food and Drug Administration draft guidance describes the use of a rapid test (RT) to enhance platelet transfusion safety and availability. This study reports a 113-month experience of screening of apheresis platelets (APs) by RT. STUDY DESIGN AND METHODS:From July 2008 to October 2015, all APs und...

journal_title：Transfusion

authors： Ruby KN,Thomasson RR,Szczepiorkowski ZM,Dunbar NM

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Early identification of acute traumatic coagulopathy is a key challenge during initial management to determine whether to initiate early hemostatic support. We assessed the performance of prothrombin time (PT) at point-of-care in trauma patients to detect moderate and severe coagulopathy on admission. STUDY...

journal_title：Transfusion

authors： Deras P,Nouri J,Martinez O,Aubry E,Capdevila X,Charbit J

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The intrinsic properties of polypeptide blood group antigens that determine their relative immunogenicities are unknown. Because size, composition, charge, dose, and epitope glycosylation affect the immunogenicity of other polypeptides, we examined whether similar properties were related to the immunogenicit...

journal_title：Transfusion

authors： Howe JG,Stack G

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Research with primary human white blood cell (WBC) subpopulations requires high quantity, quality, and functionality of peripheral blood mononuclear cells (PBMCs) as a source to further characterize cellular subpopulations such as T and B lymphocytes, monocytes, or natural killer cells. Apart from buffy coat...

journal_title：Transfusion

authors： Knörck A,Marx S,Friedmann KS,Zöphel S,Lieblang L,Hässig C,Müller I,Pilch J,Sester U,Hoth M,Eichler H,Sester M,Schwarz EC

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Fever accompanying vaso-occlusive crisis is a common presentation in patients with sickle cell disease (SCD) and carries a broad differential diagnosis. Here, we report a case of transfusion-transmitted malaria in a patient with SCD presenting with acute vaso-occlusive crisis and rapidly decompensating to mu...

journal_title：Transfusion

authors： Maier CL,Gross PJ,Dean CL,Chonat S,Ip A,McLemore M,El Rassi F,Stowell SR,Josephson CD,Fasano RM

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Chronic transfusion in sickle cell disease (SCD) remains the gold standard therapy for stroke prevention and for patients with severe disease despite adequate hydroxyurea treatment. The aim of our study was to assess the safety and efficacy of automated red blood cell exchange (aRBX) in patients with SCD pre...

journal_title：Transfusion

authors： Dedeken L,Lê PQ,Rozen L,El Kenz H,Huybrechts S,Devalck C,Diallo S,Heijmans C,Ferster A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Cord blood (CB) is a widely accepted stem cell source and its clinical utilization depends, to a great extent, on its cell content. Birth-to-clamping (BTC) time of umbilical cord determines placental transfusion to the newborn, and the remaining blood that can be collected and banked. The 2017 Committee Opin...

journal_title：Transfusion

authors： Ciubotariu R,Scaradavou A,Ciubotariu I,Tarnawski M,Lloyd S,Albano M,Dobrila L,Rubinstein P,Grunebaum A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Reported hepatitis E virus (HEV) antibody assay performance characteristics are variable. Using a subset of surplus US blood donation samples, we compared assays for detecting anti-HEV immunoglobulin M (Ig)M and IgG or total anti-HEV antibodies. STUDY DESIGN AND METHODS:Samples from 5040 random blood donati...

journal_title：Transfusion

authors： Zafrullah M,Zhang X,Tran C,Nguyen M,Kamili S,Purdy MA,Stramer SL

更新日期：2018-05-01 00:00:00

abstract：:In April 2017, a workshop sponsored by the National Heart, Lung, and Blood Institute, Division of Blood Diseases and Resources, and the Center for Translation Research and Implementation Science was held to discuss blood availability and transfusion safety in low- and middle-income countries (LMICs). The purpose of th...

journal_title：Transfusion

authors： Custer B,Zou S,Glynn SA,Makani J,Tayou Tagny C,El Ekiaby M,Sabino EC,Choudhury N,Teo D,Nelson K,Peprah E,Price L,Engelgau MM

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Although the subject of many previous studies, the importance of white blood cell (WBC) alloimmunization in granulocyte transfusion therapy has not been settled. In this study, we report the results of the effects of WBC antibodies in the RING (Resolving Infection in Neutropenia with Granulocytes) study, a r...

journal_title：Transfusion

authors： Price TH,McCullough J,Strauss RG,Ness PM,Hamza TH,Harrison RW,Assmann SF

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Antibodies to Mia , MUT, and Mur are among the most frequently identified alloantibodies in Southeast Asia. Understanding the characteristics of these antibodies in terms of induction and evanescence would aid in optimizing methods for their detection. STUDY DESIGN AND METHODS:Antibody testing results betwe...

journal_title：Transfusion

authors： Nadarajan VS

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The history of the development and implementation of the Brazilian nucleic acid testing (NAT) platform to detect and discriminate among human immunodeficiency virus (HIV), hepatitis C virus (HCV), and hepatitis B virus (HBV) infections in blood donors is described here. The results for the sensitivity, repro...

journal_title：Transfusion

authors： Rocha D,Andrade E,Godoy DT,Fontana-Maurell M,Costa E,Ribeiro M,Ferreira AGP,Brindeiro R,Tanuri A,Alvarez P

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Supply of cytomegalovirus (CMV)-seronegative blood products in Australia is an ongoing challenge. Requests for CMV-negative products are increasing with prediction that the demand will exceed supply by 2019. Clinical information evaluating how these products are being utilized by health providers within Aust...

journal_title：Transfusion

authors： Hirani R,Tohidi-Esfahani I,Mondy P,Irving DO

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The RhD blood group antigen is extremely polymorphic and the DEL phenotype represents one such class of polymorphisms. The DEL phenotype prevalent in East Asian populations arises from a synonymous substitution defined as RHD*1227A. However, initially, based on genomic and cDNA studies, the genetic basis for...

journal_title：Transfusion

authors： Lopez GH,Turner RM,McGowan EC,Schoeman EM,Scott SA,O'Brien H,Millard GM,Roulis EV,Allen AJ,Liew YW,Flower RL,Hyland CA

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Platelets (PLTs) are especially affected by the risk of bacterial contamination. Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) is an accurate method for the routine identification of bacterial isolates in microbiology laboratories. We directly applied the MALDI-TOF method to bacteria...

journal_title：Transfusion

authors： Chetouane Y,Dubourg G,Gallian P,Flaudrops C,Chiaroni J,Chabrière E,Raoult D,Camoin-Jau L

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick r...

journal_title：Transfusion

authors： Clavier B,Pouget T,Sailliol A

更新日期：2018-02-01 00:00:00

abstract：:Tunneled central venous catheters with ports are increasingly used for therapeutic apheresis procedures. Vortex ports have been used as access for therapeutic apheresis procedures, but are not ideal for therapeutic plasma exchange (TPE) procedures due to lower flow rates. We performed an in vitro experiment to compare...

journal_title：Transfusion

authors： De Simone N,Sarode R

更新日期：2018-02-01 00:00:00

abstract：:After 30 years of hematopoietic stem cell use for various indications, umbilical cord blood is considered as an established source of cells with marrow and postmobilization peripheral blood. The limited number of cells still remains a problematic element restricting their use, especially in adults who require to be gr...

journal_title：Transfusion

authors： Faivre L,Couzin C,Boucher H,Domet T,Desproges A,Sibony O,Bechard M,Vanneaux V,Larghero J,Cras A

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The overall number of red blood cell (RBC) units distributed to hospitals throughout the world and in the United States has decreased lately. This study was performed to determine if the number of antigen-negative RBC units distributed to hospitals has followed this trend. STUDY DESIGN AND METHODS:Stratifie...

journal_title：Transfusion

authors： Yazer MH,Anani WQ,Denomme GA,Karafin MS,Sayers M,Shaz BH,Biomedical Excellence for Safer Transfusion (BEST) Collaborative.

更新日期：2018-01-01 00:00:00

abstract：:The US Food and Drug Administration (FDA) held a workshop on red blood cell (RBC) product regulatory science on October 6 and 7, 2016, at the Natcher Conference Center on the National Institutes of Health (NIH) Campus in Bethesda, Maryland. The workshop was supported by the National Heart, Lung, and Blood Institute, N...

journal_title：Transfusion

authors： Vostal JG,Buehler PW,Gelderman MP,Alayash AI,Doctor A,Zimring JC,Glynn SA,Hess JR,Klein H,Acker JP,Spinella PC,D'Alessandro A,Palsson B,Raife TJ,Busch MP,McMahon TJ,Intaglietta M,Swartz HM,Dubick MA,Cardin S,Patel

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Genomewide association studies have reported alleles in the ABO locus to be associated with ferritin levels. These studies warrant the investigation of a possible association between the ABO blood group and ferritin levels. We aimed to explore if ABO blood group is associated with iron stores expressed as fe...

journal_title：Transfusion

authors： Rigas AS,Berkfors AA,Pedersen OB,Sørensen E,Nielsen KR,Larsen MH,Paarup HM,Wandall HH,Erikstrup C,Hjalgrim H,Ullum H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Congenital thrombotic thrombocytopenic purpura (TTP) may not be recognized until organ failure related to the microvascular thrombosis occurs. Kidney failure may be the initial presenting clinical feature. Kidney transplantation has been contraindicated because of the assumption that the continuing microvasc...

journal_title：Transfusion

authors： Fattah H,Kumar D,George JN,Massey HD,King AL,Friedman KD,Gupta G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Effective donor skin disinfection is essential in preventing bacterial contamination of blood components with skin flora bacteria like Staphylococcus epidermidis. Cell aggregates of S. epidermidis (biofilms) are found on the skin and are resistant to the commonly used donor skin disinfectants chlorhexidine-g...

journal_title：Transfusion

authors： Alabdullatif M,Boujezza I,Mekni M,Taha M,Kumaran D,Yi QL,Landoulsi A,Ramirez-Arcos S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) alloimmunization occurs at a high frequency in sickle cell anemia (SCA) despite serologic matching for Rh (C/c, E/e) and K antigens. RBC minor antigen genotyping allows for prediction of antigens and RH variants that may lead to alloimmunization. STUDY DESIGN AND METHODS:RBC antigen gen...

journal_title：Transfusion

authors： Yee MEM,Josephson CD,Winkler AM,Webb J,Luban NLC,Leong T,Stowell SR,Fasano RM

更新日期：2017-11-01 00:00:00